Noboru Asada Selected Research

Therapeutics

3/2024	A phase 1/2 study of NS-87/CPX-351 (cytarabine and daunorubicin liposome) in Japanese patients with high-risk acute myeloid leukemia.
2/2024	Chimeric antigen receptor T-cell therapy after COVID-19 in refractory high-grade B-cell lymphoma.
1/2023	Negative Prognostic Impact of High-Dose or Long-Term Corticosteroid Use in Patients with Relapsed or Refractory B-Cell Lymphoma Who Received Tisagenlecleucel.
1/2023	Bone marrow microenvironment disruption and sustained inflammation with prolonged haematologic toxicity after CAR T-cell therapy.
1/2023	Efficient granulocyte collection method using high concentrations of medium molecular weight hydroxyethyl starch.
12/2022	Successful neutrophil engraftment supported by granulocyte transfusion in adult allogeneic transplant patients with peri-transplant active infection.
7/2022	Chronic active Epstein-Barr virus infection presenting as refractory chronic sinusitis.
9/2020	Persistent hypogammaglobulinemia due to immunoglobulin class switch impairment by peri-transplant rituximab therapy.
1/2018	A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche.
12/2007	Successful combined use of tranexamic acid and unfractionated heparin for life-threatening bleeding associated with intravascular coagulation in a patient with chronic myelogenous leukemia in blast crisis.

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Noboru Asada Research Topics

Disease

7	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 03/2024 - 03/2006
6	Neoplasms (Cancer) 02/2024 - 10/2020
4	Infections 02/2024 - 06/2021
4	Hematologic Neoplasms (Hematological Malignancy) 01/2024 - 03/2006
4	Lymphoma (Lymphomas) 01/2023 - 01/2007
4	Leukemia 01/2021 - 12/2007
3	Inflammation (Inflammations) 01/2023 - 02/2014
3	Hypoxia (Hypoxemia) 12/2022 - 01/2007
3	Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated) 03/2021 - 10/2020
2	B-Cell Lymphoma (Lymphoma, B Cell) 02/2024 - 01/2023
2	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 12/2023 - 01/2023
2	Bronchiolitis Obliterans Syndrome 01/2023 - 01/2021
2	Cytopenia 01/2023 - 09/2020
2	Graft vs Host Disease (Graft-Versus-Host Disease) 04/2022 - 01/2021
2	Thrombocytopenia (Thrombopenia) 01/2022 - 03/2008
2	Hemorrhage 04/2021 - 12/2007
2	Osteosclerosis 11/2019 - 04/2010
2	Nerve Degeneration 04/2019 - 01/2018
2	Trichosporonosis 08/2006 - 03/2006
1	COVID-19 02/2024
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2024
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2023
1	Neutropenia 01/2023
1	Cytokine Release Syndrome 01/2023
1	Body Weight (Weight, Body) 01/2023
1	Hemolysis 12/2022
1	Disease Progression 12/2022
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 12/2022
1	Fibrosis (Cirrhosis) 12/2022
1	Sinusitis 07/2022
1	Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome) 07/2022
1	Measles 06/2022
1	Chickenpox 06/2022
1	Herpes Zoster 06/2022
1	Rubella (German Measles) 06/2022
1	Mumps 06/2022
1	Wilms Tumor (Wilm's Tumor) 04/2022
1	Constipation 01/2022
1	Febrile Neutropenia 01/2022
1	Chorea (Rheumatic Chorea) 10/2021
1	Sepsis (Septicemia) 06/2021
1	Hemophilia A (Haemophilia) 04/2021
1	Hepatitis C 04/2021
1	Hepatocellular Carcinoma (Hepatoma) 04/2021
1	acquired Factor 8 deficiency 04/2021
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2021
1	Philadelphia Chromosome 01/2021
1	Hepatic Veno-Occlusive Disease (Disease, Hepatic Veno-Occlusive) 01/2021

Drug/Important Bio-Agent (IBA)

4	CytokinesIBA 01/2023 - 02/2014
4	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2023 - 01/2021
4	Rituximab (Mabthera)FDA Link 12/2020 - 01/2007
3	Cytarabine (Cytosar-U)FDA LinkGeneric 03/2024 - 09/2022
3	venetoclaxIBA 06/2023 - 01/2022
3	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 12/2022 - 01/2017
2	Chimeric Antigen ReceptorsIBA 02/2024 - 01/2023
2	fludarabineIBA 09/2022 - 01/2021
2	Azacitidine (5 Azacytidine)FDA Link 09/2022 - 01/2022
2	AcidsIBA 03/2021 - 10/2020
2	Adrenergic Agents (Adrenergic Drugs)IBA 04/2019 - 01/2018
2	Micafungin (FK463)FDA Link 08/2006 - 03/2006
1	Liposomes (Liposome)IBA 03/2024
1	Daunorubicin (Cerubidine)FDA LinkGeneric 03/2024
1	Antiviral Agents (Antivirals)IBA 02/2024
1	cilgavimabIBA 02/2024
1	tixagevimabIBA 02/2024
1	Antineoplastic Agents (Antineoplastics)IBA 01/2024
1	Monoterpenes (Monoterpenoids)IBA 01/2024
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2024
1	carboxyl radical (COO-)IBA 12/2023
1	ErbB Receptors (EGF Receptor)IBA 10/2023
1	Tyrosine Kinase InhibitorsIBA 10/2023
1	Retinoblastoma ProteinIBA 10/2023
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2023
1	tisagenlecleucelIBA 01/2023
1	RNA (Ribonucleic Acid)IBA 01/2023
1	Bleomycin (Blenoxane)FDA LinkGeneric 12/2022
1	Neuropeptide YIBA 12/2022
1	Hemoglobins (Hemoglobin)IBA 12/2022
1	plerixafor FDA Link 12/2022
1	neuropeptide Y-Y1 receptorIBA 12/2022
1	Messenger RNA (mRNA)IBA 04/2022
1	Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA 09/2021
1	Factor VIII (Coagulation Factor VIII)IBA 04/2021
1	Factor VIIa (Activated Factor VII)IBA 04/2021
1	Oxygen (Dioxygen)IBA 01/2021
1	Galactosylceramides (Galactocerebrosides)IBA 01/2021
1	Alkylating AgentsIBA 01/2021
1	LigandsIBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 10/2020

Therapy/Procedure

12	Therapeutics 03/2024 - 03/2006
9	Drug Therapy (Chemotherapy) 02/2024 - 03/2008
6	Hematopoietic Stem Cell Transplantation 12/2022 - 09/2020
5	Transplantation 01/2023 - 04/2010
2	Photochemotherapy (Photodynamic Therapy) 03/2021 - 10/2020
2	Bone Marrow Transplantation (Transplantation, Bone Marrow) 06/2014 - 12/2007
1	Peripheral Blood Stem Cell Transplantation (Peripheral Stem Cell Transplantation) 04/2022
1	Segmental Mastectomy (Lumpectomy) 04/2021
1	Hepatectomy 04/2021
1	Salvage Therapy 01/2021
1	Photopheresis 10/2020